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& Jcker, M

By maintaining intestinal barrier integrity and inhibiting ileal inflammatory chemicals, kefir may prevent to mucosal leakage and systemic inflammation (133)

10.1172/jci.insight.174575 58 Owusu-AnsahA.IhunnahC

Although for most of the missense cases, their contribution to the pathogenesis is not well defined, the W7R and A9D mutations in the signal sequence have been shown to affect mRNA stability, sorting, and/or secretion of PGRN [20, 21]