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It catalyzes the recovery of tetrahydrofolate, which is an essential reaction for the de novo synthesis of glycine, among others [37]

O., Asare, P

2.1.6 CD8 + T cells Although the majority of the infiltrated T cells in SG of SS patients are CD4 positive, the frequency of CD4 + T cells is decreased along with the progression of the disease ( + T cells was identified to be either stable or even slightly elevated in severe tissue damage ( + T cells may play a role in the inflammatory process of pSS

Several decades later, in 1996, the first link between -syn and the PD phenotype was established with the identification of the A53T point mutation on chromosome 4q21-23 (Polymeropoulos et al., 1996)