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The availability of these compounds ultimately influences the metabolism of methionine and S-adenosyl methionine (SAM) [10], which is formed from methyl groups and is the primary methyl donor for several methyltransferases within the organism [11]

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For metagenome-associated multivariate data, we first compared prokaryotic and fungal communities by calculating unrooted phylogenetic Neighbour-Nets 63 using weighted UniFrac distances and compared the 16S rRNA-conditional bacterial assemblages using KR distances