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ElkafrawyNYounesKNaguibABadrHKamal ZewainSKamelMet alAntihypertensive efficacy and safety of a standardized herbal medicinal product of Hibiscus sabdariffa and olea Europaea extracts (NW Roselle): a phase-ii, randomized, double-blind, captopril-controlled clinical trial

Psychopharmacology 169 (1), 108114

While macrophage-specific knockout of ATP citrate lyase stabilized murine plaques and showed dysregulated cholesterol and fatty acid metabolism, main effects seemed to be exerted via changes in apoptosis ( Fumarate accumulation in -glucan trained monocytes increases histone methylation associated with an increased pro-inflammatory gene transcription of TNF and IL-6 (Liu et al., 2017)

It signals via a completely different biochemical pathway than GHRH