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Phase 2 trial data (Jastreboff et al., NEJM 2023) demonstrated average weight reductions of approximately 1724% over 48 weeks notably higher than currently approved GLP-1 receptor agonists such as semaglutide, though direct comparisons are limited by differences in trial populations and designs

Research Background Research on HGH Fragment 176-191 has demonstrated its ability to stimulate lipolysis in adipocytes at a comparable rate to full-length hGH, while lacking the diabetogenic and growth-promoting properties

[1] This discomfort is usually transient and can be minimized by using proper technique and allowing the solution to come to room temperature before injection