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Future Direction and Call to Action The current evidence gap presents an opportunity for orthopaedic investigators to establish high-quality prospective registries evaluating peptide exposure in real-world musculoskeletal populations

All native peptides are composed of a flexible N-terminus, a C-terminal amphipathic -helix and an amidated C-terminus (Larhammar, 1996

Generally, drops of more than 20 mmHg systolic or 10 mmHg diastolic warrant attention, particularly if accompanied by symptoms like dizziness or fatigue