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GI-sensitive individuals benefit from extended 16-20 week titrations and may find optimal results at maintenance doses of 1.8-2.0mg weekly rather than pushing to 2.4mg

Non-medication approaches include: Engaging in physical activity such as strength training, cardio, stretching, or water-based exercisea healthcare provider can recommend the type of exercise that may work best for you Using a mobility aid such as a walking stick or knee or foot braces Applying heat or cold to the painful joints Non-steroidal anti-inflammatory drugs (NSAIDs)such as Advil (ibuprofen) or Aleve (naproxen)are typically the first recommended pain relievers

You may also get it from a licensed physician as an alternative therapy if other treatments dont work

Short-term administration of nicotinamide mononucleotide preserves cardiac mitochondrial homeostasis and prevents heart failure