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Moreover, omega-3 PUFAs can enhance a cells endogenous antioxidant capabilities through multiple mechanisms: they can increase the activity of enzymes involved in antioxidant defense, such as glutathione peroxidase and superoxide dismutase, thus enhancing resistance to ROS-induced damage and reducing lipid peroxidation

Meanwhile, another RCT in 14 patients with schizophrenia examined the first-night effect that represents sleep disturbances under the unfamiliar sleeping environment using polysomnography [48]