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Description

GDF15 regulates the metabolic pathways of macrophages, acquiring an anti-inflammatory function dependent on oxidative phosphorylation, reducing the expression of pro-inflammatory factors, and decreasing the infiltration of monocytes and neutrophils into the liver, thereby alleviating liver inflammation [174, 175]

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Their status is closely linked to their mechanisms

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Fukuda A, Deshpande SB, Shimano Y, Nishino H

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Cardiac complications in Thalassemia throughout the lifespan: victories and challenges [J]

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