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Stress management: Since emotional stress can be a trigger, stress management techniques can be a helpful part of a comprehensive management plan [3]

Pulse Dosing and Cycling Strategies Some practitioners recommend pulse dosing strategies that alternate between higher and lower doses or cycle between treatment periods and rest periods

Icariin demonstrates a protective effect against gentamicin-induced ototoxicity in HEI-OC1 cells and cochlear explants through AMPK-SIRT3 signaling cascade activation, thereby offering a novel approach for addressing ototoxicity resulting from aminoglycoside antibiotics (Hu and Ma 2021)