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Preclinical and clinical assessment of inhaled levodopa for OFF episodes in Parkinsons disease

Elevated ROS levels have been observed in various cancers and have been linked to the activation of signaling pathways involved in cancer initiation and progression, including the mitogen-activated protein kinase/Erk, phosphatidylinositol-3-kinase (PI3K)/Akt, and IB kinase/NF-B pathways (83)