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Conversely, in large controlled clinical trials involving patients with moderate to severe stable COPD, the combination of fluticasone furoate/vilanterol enhanced lung function, reduced respiratory symptoms, and decreased the number of COPD exacerbations, including hospitalizations related to COPD [23]

Osteoporosis Osteoporosis is characterised by a loss of bone mass that leads to a weakening of the bone and an increased risk of fractures

Moreover, UV radiation decreases the thioredoxin reductase activity as well as thioredoxin level, thereby lowering the effectiveness of thioredoxin-dependent antioxidant system, and exposing the thiol groups of the oxidized proteins to less effective reduction

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