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In general, the protective mechanism of L-theanine for the liver and kidney is to inhibit the NF-B pathway, regulate pro-inflammatory cytokines, such as IL-1, IL-6, IL-10, and TNF, and finally regulate the activities of AST, ALT, T-SOD, and other related enzymes, to effectively protect the liver and kidney and deal with liver and kidney injury caused by different reasons

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In the liver, a major site of GSH metabolism, this consists of: a) extensive catabolism of GSH within biliary spaces (Ballatori et al., 1986b, 1988, 1989), as well as within sinusoidal compartments of some species (Hinchman and Ballatori, 1990, 1994), b) direct hepatic reabsorption of some of the breakdown products (Ballatori et al., 1986a, 1988

Suryawanshi AR, Khan SA, Gajbhiye RK et al (2011) Differential proteomics leads to identification of domain-specific epididymal sperm proteins