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First, the overlapped SNO proteins between the SA-treated mice, Shank3 ASD mutant mice, and P301S AD mutant mice were identified (Fig

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Besides cellular senescence, the phenotype of aging podocyte is distinguished by alterations in ultrastructure and functionality, oxidative, cellular, and endoplasmic reticulum stress, and hypertrophy, alongside diminished autophagy, and the heightened manifestation of genes associated with aging

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