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These differentially hydroxymethylated regions (DhMRs) were enriched with genes associated with neurogenesis and neuronal survival (Kumar et al., 2018), involving pathways such as Wnt / - catenin / Sox , NMDAR / calcium / CREB , and GABA type A receptor pathways

However, other PFAS, including chemicals in AFFF with nonfluorinated alkyl groups (polyfluorinated substances), are likely amenable to biotransformation