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Untargeted multi-omic analysis of colorectal cancer-specific exosomes reveals joint pathways of colorectal cancer in both clinical samples and cell culture

The disruption in mitochondrial activity, such as mitochondrial transfer from stromal cells to tumor cells, is crucial to tumor cell survival 34 , and the malate-aspartate shuttle constitutes a significant source of ROS 35

The bacterial SUF system contains two complexes: SufSE (where SufS is Cys desulfurase and SufE is sulfur transferase), and SufBC 2 D (the scaffold complex)

NMS increased iNOS expression, suggesting elevated reactive oxygen and nitrogen species