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Arch Neurol 60:10821088 Sarchielli P, Di Filippo M, Candeliere A, Chiasserini D, Mattioni A, Tenaglia S, Bonucci M, Calabresi P (2007) Expression of ionotropic glutamate receptor GLUR3 and effects of glutamate on MBP- and MOG-specific lymphocyte activation and chemotactic migration in multiple sclerosis patients

These effects included reduction of vWF multimer size, removal of ULVWF strings from the endothelial surface, and marked shortening of the time to reestablish normal blood flow in the microvasculature of ADAMTS13-deficient mice challenged to secrete vWF