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About This Issue Although thyroid disorders are common, decompensated hypothyroidism and thyroid storm represent the rare, life-threatening, extreme ends of the spectrum of thyroid dysfunction

One critical mechanism through which gut bacteria influence inflammation involves the production of short-chain fatty acids (SCFAs), such as butyrate, acetate, and propionate (Zhou et al., 2024)

49 Moreover, administration of high doses of IL-1 fails to exacerbate APAP-induced liver injury, further suggesting a limited role of IL-1 signaling in the pathogenesis of APAP hepatotoxicity