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[DOI] [PMC free article] [PubMed] [Google Scholar] 34.Coleman ME, DeMayo F, Yin KC, et al

Increased levels of miR-144 have been found in a subset of HbSS patients with typical severe anemia and reduced NRF2 protein levels, causing a reduction of GSH regeneration and impairing cell response to OS, thereby providing a possible mechanism for the increased anemia severity seen in these patients [221]