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ClinicalTrials.gov (2011)

6.5 Reaction with cellular macromolecules 6.5.1 Proteins Acetaldehyde can react with nucleophilic groups, such as amino, hydroxyl, and sulfydryl groups, through nucleophilic attack on the carbonyl carbon atom of acetaldehyde to give both stable and unstable adducts (Tuma et al., 1984)