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Therefore, HBO's capacity to fine-tune autophagic activitypromoting its protective role in cellular clearance while curtailing its detrimental progression to programmed cell deathhighlights its potential not only in focal ischemia but also in addressing global cerebral injury following cardiac arrest and CPR, where dysregulated autophagy significantly contributes to neuronal damage

[] Explanations for the sex differences include differences in anatomy, strength, reflex times and hormones

doi: 10.1056/NEJMoa1809944 67

Adverse reactions that occurred more frequently with EGRIFTA relative to placebo and had an incidence 1% during the first 26 weeks across all studies are presented in Table 1