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This alteration is accompanied by the activation of reactive astrocytes, which contribute to neuroinflammatory impairments (Hou et al., 2019)

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The findings indicated that ADSC-Exo could regulate the Atf3/Slc7a11 axis, reduce lipid peroxidation and iron accumulation, inhibit inflammatory microenvironments, and promote neuronal survival, significantly improving neurofunction in I/R-injured mice (Wang et al., 2024)