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While specialized neurons are located at the back of the eye in the retina, the front of the eye, composed of cornea, conjunctiva, and its adnexae, including Meibomian glands, together with the lens and anterior chamber, is responsible for 2/3 of the refractive power of the eye 1

Together with our reporter analysis (Table 1, see Additional file 2: Figure S3), this suggests that while some genes are more broadly required for stress-induced phase 2 detoxification gene expression, others may be specifically required for the stress-induced expression of gcs-1 (Figure 2B,C)

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