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LC-MS LC-MS was performed using a Vanquish Ultra High-performance LC system coupled to an Orbitrap ID-X Tribrid mass spectrometer (Thermo Fisher), equipped with a heated electrospray ionization (H-ESI) source capable of both positive and negative modes simultaneously (32)

Table 1 summarizes the information presented in these studies

5-Amino-1MQ is a small molecule compound studied for its inhibitory effect on nicotinamide N-methyltransferase (NNMT), a key enzyme in methylation and cellular energy regulation

According to the Crohns & Colitis Foundation of America (CCFA), inflammatory bowel disease (IBD), which includes both Crohns disease and ulcerative colitis, affects as many as 1.6 million people in the United States