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Nrf2 represents the first line of defense and cellular response to oxidative stress and is activated by a mild increase in the level of ROS/RNS

Despite the well-established increase in IFP within breast tumors, our understanding of how breast cancer cells respond to this physical stimulus remains elusive due to the scarcity of reliable in vitro platforms that permit adjustment of pressure independent of changes in pH or the dissolved concentration of gases

Niccolai E, Baldi S, Ricci F et al (2019) Evaluation and comparison of short chain fatty acids composition in gut diseases