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On the other hand, non-proteinaceous substrates are needed to be further explored

Biosci Biotechnol Biochem 79(10):16981701

Without adequate glutathione, the central nervous system cannot protect its delicate neural pathways from the inflammatory cascade triggered by the viral invader

Given the established role of autophagy in restraining inflammasome activation through removal of damaged mitochondria and inflammasome components [7,8,9, 54,55,56,57,58], the present findings support a pathological feedback loop in which impaired autophagy permits sustained inflammatory activation