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Innate immunity gone awry: Linking microbial infections to chronic inflammation and cancer

Increased levels of total lipids, cholesterol, and TG in this study could indicate high lipid peroxidation, which is associated with glycolipid metabolism disorders, loss of cell membrane integrity, and increased energy demand, resulting in cell damage, lipid accumulation, and apoptosis (Saad et al

The observation of a hook effect is context-dependent and influenced by the relative concentrations of all 3 members of a ternary complex 52 , which may differ between native cellular environments and reconstituted biochemical assays

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