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Bilirubin is presumed to be transported by hepatic ligandin from the liver cell plasma membrane to the endoplasmic reticulum, at which site the conjugating enzyme, UGT1A1, is situated

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Rabbit immunizations In a first immunization study, 18 rabbits (New Zealand White, female, 3 groups, 6 animals/group) were immunized under subcontract at Covance (Denver, USA) with either 10 g AMS0232 E2 monomer, 22 g AMS0232 E2E1-I53-50A or 27 g AMS0232 E2E1-NP (equimolar to E2)

Both intracellular and extracellular growth factors can play a significant role in the development of MDR in cancer cells [11, 61, 62]