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doi: 10.1186/S13148-025-01967-0 148

But it must be acknowledged that, like heavy metals, excessive concentrations of metal ions from the aforementioned metals can induce various forms of cellular damage and apoptosis, resulting in increased wound inflammation and oxidative stress responses (Song et al., 2019)

As shown in the complex structures of PL pro ubiquitin and PL pro ISG15, SUb1 of SARS-CoV-2 PL pro preferentially binds ISG15 through a different binding mode compared with uniquitin

Rost S, Fregin A, Ivaskevicius V et al (2004) Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2