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TABLE 2 Clinical characteristics of the enrolled isolates

While the G6PD-d monocytes displayed the phenotypic hallmarks of M2 polarization (CD11b, CD209 expression), these cells were functionally deficient in M2 atheroprotective TGF and had increased expression of proinflammatory M1 cytokines TNF and MCP-1

To investigate, Huiying Li, a molecular pharmacologist at the University of California-Los Angeles, and her team decided to focus on high levels of B12 as a possible culprit, based on research from the past six decades that's linked it to higher instances of the condition