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In the following narrative, we summarize the compounds that have become more popular in HCC therapy in the last few years, which are able to inhibit HCC cells in different pathways from ferroptosis, and may play a great role in the future of hepatocellular carcinoma therapy ( Table 1 )

Acknowledgments The authors would like to dedicate this article to the defenders of Ukraine, the warriors whose health directly depends on the integrity of their intestinal wall

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The FDA approved naloxone in 1971 as a prescription-only medication for intravenous, intramuscular, and subcutaneous administration to reverse postoperative respiratory depression induced by opioid analgesics