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Aug 14: In what is expected to become a multibillion-dollar blockbuster, Pfizers BCMAxCD3 bispecific antibody Elrexfio (elranatamab-bcmm) has secured an FDA accelerated approval as another off-the-shelf treatment option for patients with relapsed or refractory multiple myeloma (RRMM) who have received at least four prior lines of therapy

[DOI] [PMC free article] [PubMed] [Google Scholar] [175].Wirth EK, Bharathi BS, Hatfield D, et al

For example, certain types of peptide linkers are designed to be cleaved by enzymes abundant in tumor cells to selectively release drugs to these cells

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