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Front Immunol (2023a) 14:1082144

Increased copper levels can upregulate inducible NO synthase (iNOS) expression, resulting in excessive NO production and peroxynitrite, a potent oxidant that causes further oxidative damage [86]

Srikiatkhachorn, A., Mathew, A

If you've been trained by your health care practitioner to administer a second dose using a second pen, select a different injection site, at least one inch or 2.5 centimeters away from the first injection site