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High exposures are required when normal absorption is impeded and are generally considered safe

Borrelli S, De Nicola L, Minutolo R, Perna A, Provenzano M, Argentino G, Cabiddu G, Russo R, La Milia V, De Stefano T, Conte G, Garofalo C (2020) Research Group of Peritoneal Dialysis of Italian Society of Nephrology

Additionally, The tumor-suppressive role of UTX has been demonstrated in pancreatic cancer, where in vivo and in vitro studies show that enforced UTX expression inhibits pancreatic cancer cell proliferation and invasion, while UTX knockdown is associated with poor prognosis

The zinc sensing receptor, ZnR/GPR39, in health and disease