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This uncertainty creates a precautionary gap- both regulators and manufacturers may be cautious, delaying product approvals until more safety data are available

10.1016/j.toxlet.2014.04.011 54 LiS.TanH.-Y.WangN.ZhangZ.-J.LaoL.WongC.-W.et al (2015)

671,672 Upon activation, Akt enhances glucose uptake in cancer cells by promoting the surface localization of GLUT1 and inhibiting its internalization