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Mini reviews in medicinal chemistry

Perturbation of these pathways is critical to many neurological disorders (NDs) such as Alzheimers disease (AD), Parkinsons disease (PD), Multiple sclerosis (MS), Amyotrophic Lateral Sclerosis (ALS), and Cerebral ischemia, indicating their involvement in the pathogenesis and advancement of these conditions (7)

From these initial runs, we determined that GR was significantly more active, and the system was more efficient at scavenging ROS if Gpx concentration was higher than GR concentration