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Here we used such iPSC-derived complex liver organoids to assess the specific impact of ALGS-causing mutations on parenchymal and non-parenchymal liver cells, their role on bile duct formation and survival, and the interactions between signaling pathways suspected to play a role in ALGS pathophysiology

Body Disease Research: KLOW Blend is relevant for research into body diseases including obesity, type 2 diabetes, and non-alcoholic fatty liver disease, as these conditions are linked with increased gut permeability and gut-derived swelling

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In the U.S., up to 40% of white people and Hispanic people have this mutation