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2.4 The ferroptosis-inflammation vicious cycle drives chronic periodontitis Growing evidence indicates that ferroptosis can trigger inflammatory responses, while the inflammatory microenvironment further promotes ferroptosis, forming a self-amplifying vicious cycle that drives the persistent progression of chronic periodontitis

Kynurenines and depression in other neurobiological conditions Alterations in KYN metabolism extend beyond MDD and have been implicated in a range of neurobiological conditions associated with depressive symptoms, such as bipolar disorder, schizophrenia, Alzheimers disease, and acquired brain injury

Interestingly, the results revealed that all four components inhibited both the monophenolase and diphenolase activity of tyrosinase, which had smaller molecular weights, correlating with greater tyrosinase inhibitory activity

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