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(ii) the uptake and distribution of melanosome in keratinocytes and (iii) melanin and melanosome degradation and turnover of "pigmented" keratinocytes 5

[DOI] [PMC free article] [PubMed] [Google Scholar] [154].Yao Q, Cui J, Wang J, et al

Here, we report on such a dual engineering approach, where the REW substitutions in IgG1 resulted in favorable pharmacokinetics in human FcRn expressing mice, combined with increased ability to activate the classical complement pathway in an on-target manner

Thus, melatonin plays a crucial role as a potent antioxidant and DNA protectant against UVR-induced oxidative damage in human skin (83)