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doi: 10.3389/fphar.2025.1715922 Received 01 October 2025 Revised 07 November 2025 Accepted 10 November 2025 Published 26 November 2025 Volume 16 - 2025 Edited by Mahdi Vajdi, Isfahan University of Medical Sciences, Iran Reviewed by Norma Margarita De La Fuente Salcido, Autonomous University of Coahuila, Mexico Asaad Sh