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Funding This review has been funded by Foundation Foltra, Teo, Spain, grant number Foltra 2020-06

We will discuss the underlying mechanisms of cellular senescence, the progress in developing senolytics and senomorphics, and the preclinical and clinical data supporting their potential as therapeutic agents

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Supplementation also becomes necessary because certain conditions, such as exposure to chemotherapy, radiation, heavy metals, etc., require a strong antioxidant to help protect the body and rid it of these oxidative stress markers