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Activation of these receptors modulates cytokine secretion, epithelial permeability, and neutrophil recruitment, suggesting a direct pathway by which dysbiotic metabolic profiles influence local immunity

Binding agents act within the gastrointestinal tract to adsorb these compounds and facilitate fecal elimination, reducing systemic reabsorption and inflammatory signaling,,,

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Briefly, 50 l of a 26% pluronic F-127 gel (Sigma-Aldrich, P2443) (w/w, dissolved in H2O) were solidified at the bottom of a 35 mm plate and 40-45 worms were placed on top