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HIV-1 proteins, including Tat, Nef, Vpr, protease, and gp120, modulate ROS-generating systems and induce oxidative stress, thereby promoting the expression of viral genes and proinflammatory lymphokines 114,115,116

Synthesis of Glutathione Glutamate-cysteine ligase converts glutamate and cysteine into gamma-glutamylcysteine, and glutathione synthetase adds glycine to form glutathione (GSH)

Coxhead J, Kurzawa-Akanbi M, Hussain R, Pyle A, Chinnery P, Hudson G (2016) Somatic mtDNA variation is an important component of parkinsons disease

Following stimulation, thin spines were shown to acquire a full functional synapse and transit simultaneously into stable mushroom spines (Matsuzaki et al., 2004)