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In Laron dwarfism, due to the insensitivity to GH, and in GHR knock-out mice, appropriate testicular function develops later than in healthy males, but still occurred (88)

The selected GHK-Cu doses were calculated according to the concentration in human plasma (Pickart et al., 1980) and the content reported in a previous study (Park et al., 2016)

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Two of these events, including the one that led to a death, were determined to be due to severe underlying coronary artery disease, while one was determined to potentially be related to treatment