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Mass Spectrometry (MS) Protein spots displaying significant ( P 50 kDa)

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IGF-1 is released from IGFBPs by mechanisms involving extracellular matrix (ECM) binding or proteolysis in the linker domain (Schedlich et al., 2000), and 6 ( Interconnectedness of IGF and Sex Steroids Network During Development and Ageing Estrogens In adulthood, estrogen is the primary sex-steroid agonist of GH secretion in both women and men (Veldhuis et al., 2005, 2006)