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Description

DNA methylation is a process in which DNMT catalyzes the covalent binding of SAM with a methyl to form 5mC

doi: 10.1105/tpc.107.052597

The use of 2-deoxy-4-thiocytidine and its analogues as DNA hypomethylating anticancer agents

Other growth factors such as bone morphogenetic proteins (BMPs) have received FDA approval for specific indications and may represent more appropriate therapeutic choices for conditions where approved therapies are available and indicated