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According to previous studies, MSCs exert immunomodulatory effects on pro-inflammatory (M1)/pro-regenerative (M2) macrophages via the secretion of various soluble bioactive factors, such as IL-10, TGF-, prostaglandin (PGE2), tumor-necrosis-factor-inducible gene 6 protein (TSG-6), and monocyte chemoattractant protein-1 (MCP-1).[14]

Expired refers to exceeding the manufacturers shelf life or the 28-day post-puncture window the solution may still be sterile but no longer guaranteed

The volume of diluent used to reconstitute a lyophilised peptide determines the concentration of the resulting solution and, consequently, the volume required for each dose

Early publications described BPC-157 as a 15-residue fragment associated with a larger gastric peptide referred to by the researchers as BPC