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The role of the microbiome in regulating bone remodeling was shown in germ free mice (in C57BL/6 background) which have increased femoral bone density (both trabecular and cortical) when compared to conventionally raised mice [132]

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Additionally, the expression of SLC7A11 decreased, which is another factor contributing to ferroptosis sensitivity

Exogenous stimuli sources (light, ultrasound, temperature, magnetic fields) may damage the normal cells