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6.1 Niacin, BHB, butyrate: efficacy and limitations Nicotinic acid (niacin), a vitamin of the B complex, was the first agonist discovered for GPR109A (96, 97)

28 , 29 On the other hand, this lead Selye to propose the concept that the most essential role of the adrenotropic principle in the coping response was to reestablish homeostasis 22 while two other principles, thyrotropic and histaminergic, remained less emphasized

Xu et al., 2020) (Figure 4)

Cofatores Essenciais para o Ciclo da Glutationa Vitamina B2 (Riboflavina) Participa da enzima glutationa redutase, responsvel por regenerar a glutationa oxidada (GSSG) em sua forma ativa (GSH)