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Increased labile iron and subsequent lipid peroxidation due to ROS production are key features of ferroptosis, an iron-dependent cell death mechanism (James et al., 2015)

Five-year overall survival for patients with advanced nonsmall-cell lung cancer treated with pembrolizumab: results from the phase I KEYNOTE-001 study

In addition, research has indicated that frequent consumption of fried foods, such as fried potatoes, is associated with an increased risk of anxiety and depression, closely related to lipid metabolism dysfunction and neuroinflammation mediated by acrylamide, a representative pollutant in fried foods [241]